Liver cancers armed with many strategies for evading immune response
(Medical Xpress)—Researchers at Roswell Park Cancer Institute (RPCI) have published findings that help explain how a common and particularly resilient form of liver cancer evades the body's natural...
View ArticleImmune protein could stop diabetes in its tracks
Melbourne researchers have identified an immune protein that has the potential to stop or reverse the development of type 1 diabetes in its early stages, before insulin-producing cells have been...
View ArticleGround breaking cancer research finds immune system link
(Medical Xpress)—Curtin University researchers have found evidence that targeting specific cells in the body can reverse the effects of cancer on the immune system.
View ArticleUCLA stem cell gene therapy for sickle cell disease advances toward clinical...
Researchers at UCLA's Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have successfully established the foundation for using hematopoietic (blood-producing) stem cells from...
View ArticleMaintaining immune balance involves an unconventional mechanism of T cell...
New findings from St. Jude Children's Research Hospital reveal an unconventional control mechanism involved in the production of specialized T cells that play a critical role in maintaining immune...
View ArticleScientists discover kill-switch controls immune-suppressing cells
Scientists have uncovered the mechanism that controls whether cells that are able to suppress immune responses live or die.
View ArticleIs a common food fungus worsening the AIDS epidemic?
A type of fungus coating much of the stored corn, wheat, rice and nuts in developing countries may be quietly worsening the AIDS epidemic, according to a paper published in the World Mycotoxin Journal.
View ArticleResearchers restore immune function in spinal injured mice
In a new study, researchers at The Center for Brain and Spinal Cord Repair at The Ohio State University Wexner Medical Center show that is possible to restore immune function in spinal injured mice.
View ArticleSome immune cells appear to aid cancer cell growth, study finds
The immune system is normally known for protecting the body from illness. But a subset of immune cells appear to be doing more harm than good.
View ArticleStudy uncovers new explanation for infection susceptibility in newborns
Cells that allow helpful bacteria to safely colonize the intestines of newborn infants also suppress their immune systems to make them more vulnerable to infections, according to new research in Nature.
View ArticleTeam uncovers mechanism, and possible treatment, for immune suppression in...
The mechanism which underlies the susceptibility of liver disease patients to life-threatening infection has been uncovered by Wellcome Trust-funded medical scientists, who have also suggested a...
View ArticleFor an immune cell, microgravity mimics aging
(Medical Xpress)—Telling someone to "act your age" is another way of asking him or her to behave better. Age, however, does not always bring improvements. Certain cells of the immune system tend to...
View ArticleDormant viruses re-emerge in patients with lingering sepsis, signaling immune...
A provocative study links prolonged episodes of sepsis—a life-threatening infection and leading cause of death in hospitals—to the reactivation of otherwise dormant viruses in the body.
View ArticleMajor discovery on spinal injury reveals unknown immune response
In a discovery that could dramatically affect the treatment of brain and spinal cord injuries, researchers at the University of Virginia and elsewhere have identified a previously unknown, beneficial...
View ArticleTransplant patients have high rate of cancer death
Researchers at the University of Adelaide are working to better understand how patients who receive life-saving organ transplants can be spared from dying of cancer many years later.
View ArticleResearch finds no correlation between regulatory T cells and survival in...
Using a novel methodology of epigenetic quantitative analysis, Dartmouth-Hitchcock's Norris Cotton Cancer Center's interdisciplinary team of investigators led by Camilo Fadul, MD, found no correlation...
View ArticleUncovering new functions of a gene implicated in cancer growth opens new...
Weill Cornell Medical College researchers have shown for the first time that a gene previously implicated in blood vessel formation during embryonic development and tumor growth also induces immune...
View ArticleProtein FGL2 may have potential as therapy target for brain cancer
Blocking FGL2, a protein known to promote cancer, may offer a new strategy for treating brain cancer, according to a study at The University of Texas MD Anderson Cancer Center.
View ArticleFemale immune response could hold key to new cancer therapies
An understanding of natural immune suppression mechanisms in the female reproductive tract could lead to new ways to combat cancer.
View ArticleResearchers find tumor suppressor p53 controls signaling-mediated...
A team of researchers with affiliations to a number of research centers in the U.S. has found that the protein p53 serves as a controlling mechanism for apoptotic (naturally dying) cells through the...
View ArticleResearchers find possible treatment for suppressed immunity from spine injuries
Scientists report in Nature Neuroscience they have identified an underlying cause of dangerous immune suppression in people with high level spinal cord injuries and they propose a possible treatment.
View ArticleMolecular switch controlling immune suppression may help turn up immunotherapies
Researchers at University of California San Diego School of Medicine and Moores Cancer Center have identified a strategy to maximize the effectiveness of anti-cancer immune therapy. The researchers...
View ArticleNew therapeutic vaccine approach holds promise for HIV remission
A study led by researchers at Beth Israel Deaconess Medical Center (BIDMC), in collaboration with scientists at Walter Reed Army Institute of Research (WRAIR), Janssen Vaccines & Prevention B.V.,...
View ArticleCombination therapy for glioblastoma shows promising results in early-stage...
UCLA researchers have discovered that combining a vaccine developed at UCLA with other experimental therapies and FDA-approved treatments shows promise for reducing the size of advanced brain tumors....
View ArticlehCG reduces caspase-3-dependent IL-16 expression
(HealthDay)—Human pregnancy hormone chorionic gonadotropin (hCG) triggers immune suppression by attenuating the processing and release of Caspase-3-dependent interleukin (IL)-16, according to a study...
View ArticleData show five-year response for AAT deficiency gene therapy
Data demonstrating sustained protein expression five years after a single intramuscular injection of a gene-based therapy for the treatment of alpha-1 antitrypsin (AAT) deficiency also shows...
View ArticleNew clues found to common respiratory virus
By age 2, most children have been infected with respiratory syncytial virus (RSV), which usually causes only mild cold symptoms. But people with weakened immune systems, such as infants and the...
View Article'Golden Hour' study details earliest changes to the immune system after trauma
Scientists from the University of Birmingham are carrying out pioneering research as part of a major £10 million study aimed at improving outcomes for patients who have suffered a traumatic injury.
View ArticleZika virus stifles pregnant women's weakened immune system to harm baby,...
The Zika virus, linked to congenital birth defects and miscarriages, suppresses a pregnant woman's immune system, enabling the virus to spread and increasing the chances an unborn baby will be harmed,...
View ArticleBacteria in the gut modulates response to immunotherapy in melanoma
Bacteria that live in the human digestive tract can influence how cancer responds to immunotherapy, opening a new avenue for research to improve treatment, a team led by researchers at The University...
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